Artesunate for Injection

Active Ingredients: Artesunate

Artesunate for Injection is an antimalarial drug used for the treatment of uncomplicated cases of malaria due to Plasmodium falciparum. Artesunate is generally well tolerated by patients and is a first-line treatment option for adults and children. This drug is not used for the prevention of malaria.

Artesunate has also been shown to have anti-cancer activity in the treatment of leukemia.

Artesunate is a water-soluble hemisuccinate derivative of dihydroartemisinin. It is one of the few artemisinin derivatives that is water soluble. It works by a combination of actions, including interfering with the heme group and increasing ROS (reactive oxygen species) and free radicals.

Artesunate for Injection is produced and exported as a combination kit with two diluents: 5% Sodium Bicarbonate and 0.9% Sodium Chloride. Sodium Bicarbonate helps improve the tolerability and safety of the medication, as it helps raise the pH of the reconstituted Artesunate. Sodium Chloride is a sterile solution in which the Artesunate can be dissolved, which also helps deliver electrolytes and fluids to the patient.